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KMID : 1004620190250020170
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Clinical Nursing Research
2019 Volume.25 No. 2 p.170 ~ p.178
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Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication
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Lee Su-Jin
Ju Hyeon-Ok
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Abstract
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Purpose: The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with systemic lupus erythematosus.
Methods: 128 patients aged ≥19 years, who were regular outpatients or admitted patients diagnosed with systemic lupus erythematosus at a tertiary hospital in B city, participated in this study. Data were collected by using a self-administered questionnaire. Testing of mediating effects was analyzed by a parallel redundant mediated model using the PROCESS macro for SPSS version 3.3.
Results: They scored an average of 16.71±11.13 for depression, 694.14±170.68 for self-efficacy, 3.05±4.60 for the belief about medication, and 90.14±15.37 for medication adherence. The direct effect of depression on medication adherence was not statistically significant, but the indirect effects of depression mediated with self-efficacy and belief about medication were statistically significant.
Conclusion: It is necessary to develop and apply a nursing intervention program that can not only relieve depression but also promote self-efficacy and the belief about medication with the objective of improving medication adherence among patients with systemic lupus erythematosus.
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KEYWORD
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Systemic Lupus Erythematosus, Depression, Self-Efficacy, Perception, Medication Adherence
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